In trials in mice, a therapy developed at Stanford safely and effectively treated five types of pediatric brain tumors.
Stabbing or dull? Burning? Throbbing? Constant or intermittent? How bad on a scale of 1 to 10?
Formerly conjoined twins Eva and Erika Sandoval are one step closer to going home. The 2½-year-old sisters, who were surgically separated on Dec. 6, moved from Palo Alto to UC Davis Children’s Hospital in Sacramento.
Marijuana use isn’t safe for teenagers, and pediatricians need to be ready to explain why, according to a new clinical report published this week by the American Academy of Pediatrics.
Formerly conjoined twins Erika and Eva Sandoval, who were separated December 6 are making good progress on learning to live as two people.
Using stem cells and gene therapy to treat or cure disease may still sound like science fiction, but it is moving closer and closer to fact.
When a patient has an unusual immune dysfunction, a few generalized therapies — steroid medications, for instance — are given to try to quiet the problem.
Research on anorexia nervosa often excludes boys and men, who make up about 10 percent of those affected by the serious eating disorder.
Recently, Stanford pediatric cardiologist Marlene Rabinovitch, MD, and her team published new research that advances their quest to understand a serious — and very puzzling — lung disease.
For the last several years, adolescent mental health experts from Lucile Packard Children’s Hospital Stanford have been partnering with many other community organizations to improve options for teens’ mental health care, a response to mental health crises among local teens.
In the age of genetic medicine, it’s still surprisingly difficult to diagnose rare genetic diseases, and even more complicated to identify brand-new ones. But several Stanford scientists are working on ways to change that.
If the only hope for your baby daughter lay in a brand-new experimental drug, would you want doctors to give it to her? What if she would be the first infant in the world to receive it?
For many years, scientists have known that adolescent girls are about twice as likely as boys to develop post-traumatic stress disorder after being exposed to a psychologically traumatic event. But no one has been sure why.
A Stanford team published their discovery of a hormone that signals when the body needs more fat stores. It sends its message in response to two external signals that we already knew could make people fatter.
Recently, a team of Stanford researchers was testing a new way to fight cancer when something strange happened. The team, led by pediatric radiologist Heike Daldrup-Link, MD, was studying whether tiny bits of iron could act as Trojan horses, sneaking chemotherapy into tumor cells. They tested the idea in mice, but the results were not what they expected.
For years, pediatric cardiologists have been trying to understand the origin of a puzzling congenital defect that creates a spongy texture in the heart muscle wall. Now, Stanford researchers have shown that they can use stem cell techniques to turn donated skin and blood cells from real patients into a useful tool for figuring out how the disease gets started.
One serious consequence of anorexia nervosa is that it hurts patients’ bones, but until now most studies of patients’ bone health have been conducted in girls and women. A new Stanford study asked whether anorexia might affect boys’ bones differently.
A large clinical trial, published today in The Lancet Oncology, should spare young people with a rare bone cancer from the side effects of too much chemotherapy. Current treatments for osteosarcoma, a malignant bone tumor that usually affects teenagers, are less effective than doctors would like, so in recent years they’ve sometimes added extra chemotherapy drugs to the standard regimen.
Doctors and parents can use a single approach to prevent both obesity and eating disorders in teenagers. That’s the message from new guidelines released this week by the American Academy of Pediatrics.
Stanford researchers recently published a scientific study describing how and why they’re trying to automate the diagnosis of rare genetic diseases.
Alarm fatigue is a big problem in hospitals, where automated monitors that track patients’ vital signs sound their alarms frequently, but the vast majority of alarms don’t indicate true crises. All the false alarms desensitize doctors and nurses to the beeping and can slow their responses to real emergencies.
Ever since I started my job in 2008, I’ve been hearing about the huge expansion of Lucile Packard Children’s Hospital Stanford that is slated to open in 2017. First it was an abstract idea, then a set of floor plans and renderings, then a fenced-off patch of dirt, then an enormous hole in the ground. Now the new building is a real, three-dimensional place, with floors, walls, windows, a roof.
Every day of my 1980s childhood began with orange juice, which my mom served because it was considered a good way to get our daily vitamin C. Since then, nutritionists’ thinking has changed. Daily consumption of fruit juice has been linked with childhood obesity and dental cavities, and kids are thought to be better off getting their vitamins from whole fruits. Yet some health policies haven’t kept up.
Once in a while, kids suffer grown-up medical problems such as multiple sclerosis, sleep apnea or stroke. None of these conditions are rare, but the fact that they hardly ever occur in children causes special frustrations and challenges for young patients.
Scientists who study childhood obesity often wonder how excess weight gain in kids can be prevented. Some experts suggest that prevention efforts should start in infancy, since formula-fed infants grow faster than those who are exclusively breast-fed. A study published this month in Pediatrics adds an interesting twist to the debate: The researchers found that babies fed with larger bottles between 2 and 6 months of age gained more weight.
Children respond strongly to the sound of their mothers’ voices, but until now the brain circuitry involved has been a mystery. A new Stanford study changes that, showing that moms’ voices get special treatment in a far wider variety of their children’s brain areas than researchers expected.
What would you do if your toddler had a very rare blood cancer and his treatments were failing? At what point would you decide that it was time to stop those treatments and make him as comfortable and happy as possible for whatever time he had left? That was the terrible decision faced by the parents of a young child with a form of leukemia so unusual and deadly that his doctors at Lucile Packard Children’s Hospital Stanford didn’t know if anyone had ever survived it.
When Elijah Olivas’s hand was severed in a car accident, dozens of experts from our pediatric trauma team coordinated to perform 20 hours of life- and limb-saving surgery.
Doctors would love to be able to predict and prevent preterm births. Right now, they mostly can’t. But research at the March of Dimes Prematurity Research Center at Stanford University is poised to change that.
Years ago, as a college varsity swimmer, I was surprised when one of my teammates told me she had struggled with an eating disorder. I knew this was a common problem in sports such as gymnastics and figure skating, where an athlete’s appearance is constantly judged, but had assumed – wrongly – that a sport where speed trumped glamour would confer protection against disordered eating.
When children who’ve been ill or injured go home from the hospital, they often carry fond memories of their child life specialists, the folks who brought toys and games to their bedsides, explained medical procedures in a non-scary way, and helped their families worry less.
What’s the first step in getting help for a child who may have autism? Discouragingly, the answer is often “A long wait.” But Stanford systems biologist Dennis Wall, PhD, wants to change that. His research team is using a big-data approach to devise simple questionnaires that enable parents and primary-care doctors to screen children for developmental disorders using a mobile device.
Stanford researchers have invented a new technique to detect cystic fibrosis in infants. The test, described in a paper published today in The Journal of Molecular Diagnostics, is more comprehensive, faster and cheaper than current newborn screening methods.
Linda Luna was five months pregnant with her first child when she got the bad news: Ultrasound scans showed a deadly defect in her baby boy’s heart. He had a 90 percent chance of dying before or just after birth. But thanks to a groundbreaking treatment at Lucile Packard Children’s Hospital Stanford, two-month-old baby Liam, who just went home to San Jose last week, is beating those odds.
This week, U.S. News and World Report released their 2016 ranking of the best diets. For their story on healthy eating for teenagers, Neville Golden, MD, division chief of adolescent medicine at Lucile Packard Children’s Hospital Stanford, explained how diet can affect teens’ brains and moods.
Attention-focusing brain networks interact more weakly than usual in kids with attention deficit hyperactivity disorder, new Stanford research shows. The research, published online this week in Biological Psychiatry, is part of an ongoing effort to figure out how the brain differs from normal in people with ADHD.
If you’ve ever plunged your hand into a tub of ice water, you know about the overlap between cold and pain: That deep, biting ache makes you want to get your hand out of the water – fast. While the protective value of that sensation is obvious, scientists have always been a bit mystified by how pain-sensing nerves register cold temperatures. But now, Stanford research on a family with an extremely unusual gene mutation may help clarify what’s going on.
Today, NPR’s Morning Edition featured an in-depth story on the evolution of decision-making in neonatal intensive care units – hospital nurseries for the sickest infants. Parents now have much more say in their babies’ care than in the past, and Stanford experts who were on the front lines of the change, including William Benitz, MD, chief of neonatology at Lucile Packard Children’s Hospital Stanford, explained how it happened.
When Danah Jewett’s 5-year-old son, Dylan, was dying from a brain tumor in 2008, she wanted to know if there was anything her family could do to help other children who might someday face the same terrible diagnosis. Yes, said Dylan’s doctor, Michelle Monje, MD, PhD: Would you be willing to donate his tumor for cancer research after his death?
When Victor Carrion, MD, was a pediatric psychiatry fellow in the mid-1990s, he had an “a-ha” moment about some of his poorly behaved patients that set the trajectory of his career. These kids had been traumatized, and the adults around them didn’t recognize it.
“Our children are in trouble because we’ve outsourced the job of feeding them,” says Stanford child nutrition expert Maya Adam, MD. To tackle the problem, Adam is spreading a refreshing message: Forget celebrity-chef culture and food fads, and just cook for your kids. Her new book shares stories about how parents around the world find a healthy approach to feeding their children.
One little-known fact about children’s hospitals: A number of their patients are not children. Local grandfather Sang Hee Yoon became one of these patients when he had a malfunctioning heart valve replaced in May, thanks to the expertise of our Adult Congenital Heart Program.
Women who are obese when they become pregnant are more likely than other expectant mothers to have a stillborn baby. A new Stanford study gives the first detailed information about which obese women are at greatest risk and which stages of pregnancy are most likely to be affected.
For many years, doctors have known that women who had diabetes during pregnancy faced an increased risk of giving birth to a baby with a congenital heart defect. But now, for the first time, researchers have shown that the risk isn’t limited to women with diabetes.
Children and teenagers with all kinds of chronic and serious conditions want normalcy in their lives, says pediatric psychologist Barbara Sourkes, PhD, who directs the palliative care program at Lucile Packard Children’s Hospital Stanford. Sourkes helps our patients and their families navigate the divide between living with a difficult diagnosis and simply being a kid. Here, she offers advice on how to help children who must “commute” back and forth between the medical world and their everyday lives.
In developing countries, well over 150,000 babies a year currently die or suffer severe brain damage from newborn jaundice. But that’s set to change, thanks to Stanford research that evaluated a safe, low-tech, inexpensive method for treating jaundice with filtered sunlight.
The hospital’s Hispanic Center for Pediatric Surgery offers patients and families the ability to receive all of their pre- and post-surgical care in Spanish. Every interaction, from registering the patient to giving post-surgical instructions, happens in the families’ first language.
Because they’re born before their lungs are fully mature, premature babies are at risk for a serious lung disease. Over the last several decades, this disease, bronchopulmonary dysplasia, has evolved into both a great medical success story and a persistent mystery. But a new Stanford study, published this week, is helping clarify the mysterious part.
Girls with autism tend to have less severe manifestations of one of the disorder’s core features, repetitive and restricted behavior, and they show brain-scan differences from boys that help explain the discrepancy, a new Stanford study has found.
Kids who suffer from anxiety about doing math problems can find relief in a program of one-on-one tutoring, which not only improves their math skills but also fixes abnormal responses in the fear circuits in their brains.
Gray matter volume and connections between several brain regions better forecast 8-year-olds’ acquisition of math skills than their performance on standard math tests, a new Stanford neuroscience study has shown.
Premature birth affects 450,000 U.S. babies each year and is the leading cause of newborn deaths. But in about half of cases, doctors never figure out what triggered premature labor in the pregnant mom. Now, there’s a new clue.
A story in Sunday’s Wall Street Journal highlights Stanford’s leadership in treating a mystifying disease in which a child suddenly develops intense psychiatric problems, often after an infection. The disease, called pediatric acute-onset neuropsychiatric syndrome, can be terribly disabling, altering kids’ personalities, interfering with their school work and making it hard for families to function.
A new Stanford study of all kids in California diagnosed with cystic fibrosis between 1991 and 2010 shows that Hispanic patients were three times as likely to die from the disease as their non-Hispanic counterparts, despite similar access to specialty care.
Today’s teenagers are familiar with the dangers of smoking conventional cigarettes, but they’re much less sure of the risks posed by marijuana and e-cigarettes, according to a Stanford study published this week in the Journal of Adolescent Health.
A tiny fraction of babies born at 22 weeks of gestation survive to childhood without major impairments or disabilities, according to a study recently published in the New England Journal of Medicine. But, although some of these babies can do well, there is variation between hospitals in the rate at which they are resuscitated after birth.
An existing drug may help treat the deadliest form of childhood brain cancer, according to a Stanford-led study published this week in Nature Medicine. The findings are the first to show an effect of any FDA-approved drug on the cancer, which is called diffuse intrinsic pontine glioma.
When Juniper French was born in April 2011, her mom had been pregnant for 23 weeks and 6 days – a little more than half of a typical 40-week pregnancy. Shortly before her birth, doctors had to try to explain the possible consequences of her very early arrival to her parents.
Eye injuries from BB guns, pellet guns and other non-powder firearms have become more common in recent years in U.S. kids, according to a new study by Stanford pediatric ophthalmologist Douglas Fredrick, MD.
Serendipity played a key role in the success of Isabella Manley’s treatment for a life-threatening tumor that made it difficult for her to breathe.
In spite of looser regulations around the sale of unpasteurized milk, it’s still unsafe to drink. That’s the message from Yvonne Maldonado, MD, chief of pediatric infectious disease at Lucile Packard Children’s Hospital Stanford, who is quoted in a new story on Today.com about the relaxation of raw-milk regulations.
The longstanding expertise of Stanford Medicine’s Fertility and Reproductive Health team has a new home: This month, the team moved to Lucile Packard Children’s Hospital Stanford and Stanford Children’s Health.
A new statement from the American Academy of Pediatrics opposing marijuana legalization was written in response to recent research on adolescent brain development and the biology of addiction, as well as a changing national climate on marijuana laws.
Silicon Valley entrepreneur and philanthropist Sean Parker has announced that he is donating $24 million to establish an allergy research center at Stanford. Scientists at the Sean N. Parker Center for Allergy Research at Stanford University will study the underlying mechanisms of all types of allergies in children and adults and will aim to develop lasting allergy cures.
A Stanford-led research team has examined how brain scans can help doctors predict preemies’ neurodevelopmental outcomes in toddlerhood. The researchers found that for babies born more than 12 weeks early who survive early infancy, brain scans performed near their original due date are better predictors than scans done near birth.
Other cardiologists are plumbers; I’m an electrician,” says Dubin. “Most cardiologists deal with structural heart disease: how the plumbing works and how the heart pumps. I focus on the electrical system that drives the pump.
It’s fall! Now that the school year is underway, you may be looking to streamline some healthy family routines, such your system for making simple and nutritious school lunches.
Finding autism caregivers and treatments is a daunting challenge for families facing a new autism diagnosis. But now there’s help. The Early Support Program for Autism, a free service with no waiting list, gives parents someone to call for up-to-date information about doctors, therapists, treatment programs and other community resources.
To conduct research on the connection between oxytocin and emotion, scientists want to assess the hormone’s levels in the brain. But sampling cerebrospinal fluid, the liquid bathing the brain, requires an invasive technique called a lumbar puncture. Measuring blood oxytocin is much easier, but some researchers have questioned whether blood oxytocin levels truly reflect what’s happening in the brain.
Autism is more than twice as common as it was 15 years ago. But the number of clinicians who treat the developmental disorder is growing more slowly than the number of new cases, prompting caregivers to look for novel ways to share their expertise as widely as possible.
Life expectancy for people with cystic fibrosis has improved dramatically in the last few decades, but those with CF still struggle with a very basic action: breathing easily. However, a new study indicates that a specific dietary supplement might stave off the decline in lung function that characterizes this genetic disease.
Scientists have long suspected that post-traumatic stress disorder raises a pregnant woman’s risk of giving birth prematurely. Now, new research from Stanford and the U.S. Department of Veterans’ Affairs confirms these suspicions.
Heavy media coverage of the Ebola epidemic in West Africa and isolated cases in the U.S. may leave parents wondering how to talk to their children about the disease. The American Academy of Pediatrics, along with Drs. Yvonne Maldonado and Victor Carrion of Stanford Children’s Health, have information to assist parents in these conversations.
Yvonne Maldonado, MD, service chief of pediatric infectious disease at Lucile Packard Children’s Hospital Stanford, answers questions about the respiratory symptoms caused by this virus. In addition, Keith Van Haren, MD, a pediatric neurologist who has been assisting closely with the California Department of Public Health’s investigation, comments on neurologic symptoms that might be associated with the virus.
A large new study comparing two treatments for anorexia nervosa offers a hopeful message to parents of teens affected by the eating disorder: Families can work with therapists to help their children recover.
Pregnant women have an unusually strong immune response to influenza, an unexpected finding that may explain why they get sicker from the flu than other healthy adults, new research from the Stanford University School of Medicine and Lucile Packard Children’s Hospital Stanford has found.
Years ago, when patients showed up at the doctor with excessive thirst, frequent urination and unexplained weight loss – in other words, the classic symptoms of diabetes mellitus.
A study published online this week in Pediatrics offers encouraging results from a large-scale effort to tackle a persistent safety problem in hospitals. The study is the first scientific investigation of a multi-hospital project to improve patient hand-offs, the times when a patient’s care is being transferred from one person to another.
As you may have heard about elsewhere, a new paper published today on the safety of childhood vaccines provides reassurance for parents and pediatricians that side effects from vaccination are rare and mostly transient. The paper, a meta-analysis appearing in Pediatrics, updates a 2011 Institute of Medicine report on childhood vaccine safety. It analyzed the results of 67 safety studies of vaccines used in the United States for children aged 6 and younger.
Three decades ago, in the early days of liver transplant, babies with liver failure usually died. Transplants were saving adults and older children, but were not offered to patients younger than 2. For these youngsters, doctors thought, the operation was too risky and difficult. But an ambitious surgeon named Carlos Esquivel changed that.
Life with type 1 diabetes requires an astonishing number of health-related decisions – about 180 per day. But patients’ vigilant monitoring of their daytime blood sugar, food intake, insulin and activity levels is perhaps less exhausting than the worries they face about getting a safe night’s sleep.
When a pregnant woman’s heart stops, two lives are threatened. Yet few caregivers know how to modify their cardiopulmonary resuscitation (CPR) technique for the expectant mom and her fetus, and few hospitals are optimally prepared for such an event.
Adolescent girls in the slums of Nairobi, Kenya, are frequent targets of sexual harassment and… Read more »
Gregory Enns, MD, pediatric geneticist at Lucile Packard Children’s Hospital Stanford and a professor of… Read more »
Pilots, astronauts and workers in other high-risk industries follow rigorous safety checklists to help them… Read more »
Living with one food allergy is a challenge; living with more than one can make… Read more »
(Updated March 25, 2014.) Keith Van Haren, MD, pediatric neurologist at Lucile Packard Children’s Hospital… Read more »
A low-cost, empowering approach makes a huge difference for high school girls in Kenya, thanks in part to a collaboration with Lucile Packard Children’s Hospital at Stanford.
Zoë Bower was 18 weeks pregnant when she and her husband, Dan Edelstein, received devastating… Read more »
From brain monitoring to therapeutic cooling, babies at risk for brain injury get their strongest start in life at Packard Children’s Neuro NICU.
Breathing traffic pollution in early pregnancy is linked to higher risk for certain serious birth defects, according to new research from the Stanford University School of Medicine.
Maurice Druzin, MD is leading efforts to equip every California hospital for saving moms’ and babies’ lives when confronted with pre-eclampsia.
Sugar may play a stronger role in the origins of diabetes than anyone realized, according… Read more »
The Graham twins from Texas are celebrating a lifesaving gift, thanks to their parents and Packard Children’s.
For parents dealing with a sick newborn, access to their baby’s condition needs to be clear and immediate. While conversations with the physician or nurse are a key source of information, Packard Children’s found another way to keep parents updated and in the loop.
Premature babies benefit from consuming breast milk, but their chance of receiving it is strongly influenced by the hospital where they spend their early days.
Teens who get in trouble with the law often have serious untreated health problems. But a strong collaborative relationship between Packard Children’s and the local juvenile justice system is helping physicians improve the health of high-risk adolescents.
A year ago, Jon and Kristi Cannon feared their young son would never smile again…. Read more »
Noah Jackson was born without a voice. Because of a rare genetic disease, his airway… Read more »